Overview

Thermal analysis may be defined as the measurement of the physical and chemical properties of materials as a function of temperature or time. Thermal Analysis instruments typically measure heat flow, weight loss, dimension change, or mechanical properties as a function of temperature. Properties characterized include melting, crystallization, glass transitions, cross-linking, oxidation, decomposition, volatilization, coefficient of thermal expansion, and modulus. This allows the user to examine end-use performance, composition, processing, stability, and molecular structure and mobility.

Netzsch DSC 214 Polyma

Heat flux DSC is of a single furnace design with a temperature sensor for each of the sample or reference pans located within the same furnace. When transitions in the sample are encountered, a temperature difference is created between sample and reference.

Main Applications

• Identify polymorphic forms of a compound
• Be used to characterize a solid dispersion system
• Determine the miscibility of the components for understanding of dissolution and release kinetics
• Analyse the dissolution of solid dispersions
• Study of solid-state kinetics such as accelerated stability, decomposition, and the effects of aging on different pharmaceutical formulations
• Range -40 to 600^oC